Glioblastoma (GBM). GBM is the most D.A.D.D.D Front Classic T Shirt and most aggressive brain cancer. It’s highly invasive, which makes complete surgical removal impossible. And because of the blood-brain barrier (BBB), it doesn’t respond to any chemotherapy. The standard-of-care entails multiple rounds of surgery and radiotherapy, yet the five year survival is lower than 5%. Pancreatic cancer (PDAC). PDAC is a notoriously stubborn cancer. The only effective treatment is a very painful and very complex operation called “the Whipple procedure”. However, only 20% of patients are eligible for such operation. And even for those lucky patients, only 20% survived more than five years. For the rest majority of patients, the chance of survival is negligible, because PDAC hardly responds to any form of chemotherapy or radiotherapy. The five year survival overall is 6%.
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Hmmm . . . not to doubt your word or anything, but are you sure your diagnosis (and your aunt’s) was pancreatic cancer and not pancreatitis? The latter is an 1000 Words Of Summer Shirt (and very painful) condition that can be completely cured or it can become chronic, controlled by diet and medications but subject to occasional flare-ups. Chronic pancreatitis can lead to pancreatic cancer, but pancreatic cancer can occur without any prior pancreatitis. Diabetes is a risk factor for both pancreatitis and pancreatic cancer. Pancreatic cancer (not to be confused with pancreatic endocrine tumors) is extremely rare in persons under 40, and it has very low survival rates — on average less than 5% of persons with pancreatic cancer will survive 5 years. That rate is somewhat better — about 16% — if the cancer is discovered when it is still localized to the pancreas, but this occurs in less than 20% of cases. Symptoms of early-stage pancreatic cancer are vague and often mistaken for other less serious conditions or even just tolerated and ignored. Given your family history with pancreatic conditions, your mother would be well advised to be extra vigilant about any possible symptoms: pain in the upper abdomen or back, loss of appetite, unexplained weight loss, fatigue, nausea and vomiting, yellow eyes or skin or dark urine (jaundice). However, almost none of these symptoms become noticeable until the disease is past the earliest, most survivable stage.
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